Reactome | Unblocking of NMDA receptors, glutamate binding and activation

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Unblocking of NMDA receptors, glutamate binding and activation Show undefined attributes

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10100299
displayName	Unblocking of NMDA receptors, glutamate binding and activation
eventOf	[Pathway:R-MMU-442755] Activation of NMDA receptors and postsynaptic events - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Pathway:R-MMU-438064] Post NMDA receptor activation events - Mus musculus
goBiologicalProcess	[GO_BiologicalProcess:1221473] regulation of NMDA receptor activity
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-MMU-438037] Membrane depolarization upon activation of Ca impermeable AMPA receptors - Mus musculus [Reaction:R-MMU-432164] Ca2+ influx into the post-synaptic cell - Mus musculus
inferredFrom	[Pathway:R-HSA-438066] Unblocking of NMDA receptors, glutamate binding and activation - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Unblocking of NMDA receptors, glutamate binding and activation
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-438066
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-442755] Activation of NMDA receptors and postsynaptic events
(precedingEvent)	[Pathway:R-MMU-438064] Post NMDA receptor activation events
(inferredTo)	[Pathway:R-HSA-438066] Unblocking of NMDA receptors, glutamate binding and activation

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