Reactome | Deadenylation of mRNA

Schema > Pathway > Entries

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10100287
displayName	Deadenylation of mRNA
eventOf	[Pathway:R-MMU-429914] Deadenylation-dependent mRNA decay - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:22761] nuclear-transcribed mRNA poly(A) tail shortening
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-MMU-430021] PAN2-PAN3 complex partially deadenylates mRNA - Mus musculus [Reaction:R-MMU-429992] PARN deadenylates mRNA - Mus musculus [Reaction:R-MMU-429955] CCR4-NOT complex deadenylates mRNA - Mus musculus
inferredFrom	[Pathway:R-HSA-429947] Deadenylation of mRNA - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Deadenylation of mRNA
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-429947
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-MMU-429914] Deadenylation-dependent mRNA decay
(inferredTo)	[Pathway:R-HSA-429947] Deadenylation of mRNA

Cite Us!