Reactome | Deadenylation-dependent mRNA decay

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Deadenylation-dependent mRNA decay Show undefined attributes

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10100285
displayName	Deadenylation-dependent mRNA decay
eventOf	[TopLevelPathway:R-MMU-8953854] Metabolism of RNA - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:22759] nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-MMU-429947] Deadenylation of mRNA - Mus musculus [Pathway:R-MMU-429958] mRNA decay by 3' to 5' exoribonuclease - Mus musculus [Pathway:R-MMU-430039] mRNA decay by 5' to 3' exoribonuclease - Mus musculus
inferredFrom	[Pathway:R-HSA-429914] Deadenylation-dependent mRNA decay - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Deadenylation-dependent mRNA decay
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-429914
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[TopLevelPathway:R-MMU-8953854] Metabolism of RNA
(hasEncapsulatedEvent)	[Pathway:R-MMU-6791312] TP53 Regulates Transcription of Cell Cycle Genes
(inferredTo)	[Pathway:R-HSA-429914] Deadenylation-dependent mRNA decay

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