Reactome | Trafficking of GluR2-containing AMPA receptors to synapse

Schema > Reaction > Entries

Trafficking of GluR2-containing AMPA receptors to synapse Show undefined attributes

catalystActivity	[CatalystActivity:9893851] ATP hydrolysis activity of NSF [cytosol]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:9864362] Wright, Adam, 2024-03-07
dbId	9893859
displayName	Trafficking of GluR2-containing AMPA receptors to synapse
eventOf	[Pathway:R-MMU-416993] Trafficking of GluR2-containing AMPA receptors - Mus musculus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-421007] Endocytosis of Ca impermeable AMPA receptors - Mus musculus
inferredFrom	[Reaction:R-HSA-416985] Trafficking of GluR2-containing AMPA receptors to synapse - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [DefinedSet:R-MMU-399713] Ca impermeable AMPA receptors [plasma membrane] [DefinedSet:R-MMU-416631] GRIP1/GRIP2 [plasma membrane] [SimpleEntity:R-ALL-29372] Pi [cytosol] [EntityWithAccessionedSequence:R-MMU-416989] PICK1 [plasma membrane]
isInDisease	false
isInferred	true
name	Trafficking of GluR2-containing AMPA receptors to synapse
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [DefinedSet:R-MMU-399713] Ca impermeable AMPA receptors [plasma membrane] [DefinedSet:R-MMU-416631] GRIP1/GRIP2 [plasma membrane] [EntityWithAccessionedSequence:R-MMU-416989] PICK1 [plasma membrane]
precedingEvent	[Reaction:R-MMU-416639] Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites - Mus musculus
regulatedBy	[NegativeRegulation:9893860] Negative regulation by 'TSPAN7:PICK1 [plasma membrane]'
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-416985
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-416993] Trafficking of GluR2-containing AMPA receptors
(precedingEvent)	[Reaction:R-MMU-421007] Endocytosis of Ca impermeable AMPA receptors
(inferredTo)	[Reaction:R-HSA-416985] Trafficking of GluR2-containing AMPA receptors to synapse