Reactome | Heterotrimeric G-protein Gi (inactive) [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-MMU-9021595] ESTG:ESRs:STRN:heterotrimeric G(i) protein [plasma membrane] - Mus musculus [Complex:R-MMU-749455] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] - Mus musculus
consumedByEvent	[Reaction:R-MMU-9021601] Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG - Mus musculus [Reaction:R-MMU-392187] Activated P2Y purinoceptor 12 binds G-protein Gi - Mus musculus [Reaction:R-MMU-749456] Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10011649
displayName	Heterotrimeric G-protein Gi (inactive) [plasma membrane]
hasComponent	[Complex:R-MMU-392164] G-protein alpha (i):GDP [plasma membrane] [Complex:R-MMU-167434] G-protein beta-gamma complex [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-392165] Heterotrimeric G-protein Gi (inactive) [plasma membrane] - Homo sapiens
maxDepth	4
name	Heterotrimeric G-protein Gi (inactive)
producedByEvent	[Reaction:R-MMU-751001] Inactive G alpha (i) reassociates with G beta:gamma - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-392165
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-MMU-9021601] Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG [Reaction:R-MMU-392187] Activated P2Y purinoceptor 12 binds G-protein Gi [Reaction:R-MMU-749456] Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi
(hasComponent)	[Complex:R-MMU-9021595] ESTG:ESRs:STRN:heterotrimeric G(i) protein [plasma membrane] [Complex:R-MMU-392184] ADP:P2RY12:G-protein Gi (inactive) [plasma membrane] [Complex:R-MMU-749455] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane]
(output)	[Reaction:R-MMU-751001] Inactive G alpha (i) reassociates with G beta:gamma
(inferredTo)	[Complex:R-HSA-392165] Heterotrimeric G-protein Gi (inactive) [plasma membrane]