Reactome | ABC-family protein mediated transport

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ABC-family protein mediated transport Show undefined attributes

created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10099939
displayName	ABC-family protein mediated transport
eventOf	[TopLevelPathway:R-MMU-382551] Transport of small molecules - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:259583] transmembrane transport
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-MMU-383190] HCO3- transport through ion channel - Mus musculus [Pathway:R-MMU-1369062] ABC transporters in lipid homeostasis - Mus musculus [Pathway:R-MMU-1369007] Mitochondrial ABC transporters - Mus musculus [Reaction:R-MMU-1454916] The ABCC family mediates organic anion transport - Mus musculus [Reaction:R-MMU-5678706] ABCB4 transports PC from plasma membrane to extracellular region - Mus musculus [BlackBoxEvent:R-MMU-8866851] CFTR transits to the plasma membrane - Mus musculus [Reaction:R-MMU-5678863] CFTR transports Cl- from cytosol to extracellular region - Mus musculus [Reaction:R-MMU-1467457] ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region - Mus musculus [Reaction:R-MMU-1467466] ABCA4 mediates atRAL transport - Mus musculus [Reaction:R-MMU-5223317] ABCB9 transports peptides from cytosol to lysosomal lumen - Mus musculus [Reaction:R-MMU-5227009] ABCF1 binds EIF2 - Mus musculus [Reaction:R-MMU-5678261] KCNJ11:ABCC9 transports K+ from extracellular region to cytosol - Mus musculus [Reaction:R-MMU-8866551] CFTR binds components of the ERAD machinery for ubiquitination and degradation - Mus musculus [Reaction:R-MMU-8866546] RNF5 and RNF185 ubiquitinate misfolded CFTR - Mus musculus [Reaction:R-MMU-8866542] VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol - Mus musculus [BlackBoxEvent:R-MMU-8866553] misfolded CFTR is degraded by the 26S proteasome - Mus musculus
inferredFrom	[Pathway:R-HSA-382556] ABC-family protein mediated transport - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	ABC-family protein mediated transport
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-382556
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[TopLevelPathway:R-MMU-382551] Transport of small molecules
(inferredTo)	[Pathway:R-HSA-382556] ABC-family protein mediated transport

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