Reactome | DNA DSBs:MRN [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-MMU-3785779] DNA DSBs:MRN:ATM dimer:KAT5 [nucleoplasm] - Mus musculus [Complex:R-MMU-5687468] DNA DSB:MRN:RBBP8 [nucleoplasm] - Mus musculus
consumedByEvent	[Reaction:R-MMU-5693612] MRN complex bound to DNA ends recruits ATM - Mus musculus [Reaction:R-MMU-5687465] MRN complex binds RBBP8 - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10049395
displayName	DNA DSBs:MRN [nucleoplasm]
hasComponent	[OtherEntity:R-ALL-75165] DNA double-strand break ends [nucleoplasm] [Complex:R-MMU-75164] MRN [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-3785763] DNA DSBs:MRN [nucleoplasm] - Homo sapiens
maxDepth	3
name	DNA DSBs:MRN
producedByEvent	[Reaction:R-MMU-3785768] MRN complex binds DNA double strand breaks - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-3785763
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-MMU-5687465] MRN complex binds RBBP8 [Reaction:R-MMU-5693612] MRN complex bound to DNA ends recruits ATM
(hasComponent)	[Complex:R-MMU-5687468] DNA DSB:MRN:RBBP8 [nucleoplasm] [Complex:R-MMU-3785779] DNA DSBs:MRN:ATM dimer:KAT5 [nucleoplasm] [Complex:R-MMU-5682035] DNA DSBs:MRN:Ac-K3016-ATM dimer:KAT5 [nucleoplasm] [Complex:R-MMU-5682055] DNA DSBs:MRN:p-S1981,Ac-K3016-ATM:KAT5 [nucleoplasm]
(inferredTo)	[Complex:R-HSA-3785763] DNA DSBs:MRN [nucleoplasm]
(output)	[Reaction:R-MMU-3785768] MRN complex binds DNA double strand breaks