Reactome | Nociceptin receptor binds to nociceptin

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Nociceptin receptor binds to nociceptin Show undefined attributes

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10009081
displayName	Nociceptin receptor binds to nociceptin
eventOf	[Pathway:R-MMU-375276] Peptide ligand-binding receptors - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-749456] Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi - Mus musculus
inferredFrom	[Reaction:R-HSA-374723] Nociceptin receptor binds to nociceptin - Homo sapiens
input	[EntityWithAccessionedSequence:R-MMU-374731] Oprl1 [plasma membrane] [EntityWithAccessionedSequence:R-MMU-374749] Pnoc [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	Nociceptin receptor binds to nociceptin
output	[Complex:R-MMU-374725] Nociceptin receptor:Nociceptin [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-374723
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-375276] Peptide ligand-binding receptors
(precedingEvent)	[Reaction:R-MMU-749456] Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi
(inferredTo)	[Reaction:R-HSA-374723] Nociceptin receptor binds to nociceptin

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