Reactome | Translocation of Ezrin to plasma membrane

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Translocation of Ezrin to plasma membrane Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10008996
displayName	Translocation of Ezrin to plasma membrane
eventOf	[Pathway:R-MMU-373752] Netrin-1 signaling - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-374664] Phosphorylation and activation of Ezrin - Mus musculus
inferredFrom	[Reaction:R-HSA-374662] Translocation of Ezrin to plasma membrane - Homo sapiens
input	[EntityWithAccessionedSequence:R-MMU-9020826] Ezr [cytosol] [SimpleEntity:R-ALL-179856] PI(4,5)P2 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Translocation of Ezrin to plasma membrane
output	[Complex:R-MMU-374570] EZR:PIP2 [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-374662
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-373752] Netrin-1 signaling
(precedingEvent)	[Reaction:R-MMU-374664] Phosphorylation and activation of Ezrin
(inferredTo)	[Reaction:R-HSA-374662] Translocation of Ezrin to plasma membrane

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