Reactome | Nephrin binds NCK

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10008724
displayName	Nephrin binds NCK
eventOf	[Pathway:R-MMU-373753] Nephrin family interactions - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-373724] Nephrin binds NCK - Homo sapiens
input	[DefinedSet:R-MMU-381949] NCK1,NCK2 [cytosol] [Complex:R-MMU-374555] p-Y1158,Y1176,Y1193,Y1217-NPHS1:KIRREL:FYN [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Nephrin binds NCK
output	[Complex:R-MMU-373677] NEPH1:p-Nephrin:Fyn:NCK [plasma membrane]
precedingEvent	[Reaction:R-MMU-373747] Phosphorylation of nephrin by FYN - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-373724
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-MMU-373753] Nephrin family interactions
(inferredTo)	[Reaction:R-HSA-373724] Nephrin binds NCK