Reactome | Amino acid transport across the plasma membrane

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Amino acid transport across the plasma membrane Show undefined attributes

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10099955
displayName	Amino acid transport across the plasma membrane
eventOf	[Pathway:R-MMU-9958863] SLC-mediated transport of amino acids - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:20641] amino acid transport
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-MMU-352158] SLC16A10-mediated uptake of aromatic amino acids - Mus musculus [Reaction:R-MMU-352119] SLC38A1 (ATA1)-mediated uptake of neutral amino acids - Mus musculus [Reaction:R-MMU-352108] SLC38A2 (ATA2)-mediated uptake of neutral amino acids - Mus musculus [Reaction:R-MMU-352174] SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine - Mus musculus [Reaction:R-MMU-352136] SLC38A4 (ATA3)-mediated uptake of arginine and lysine - Mus musculus [Reaction:R-MMU-352182] SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine - Mus musculus [Reaction:R-MMU-352103] SLC43A1 (LAT3)-mediated uptake of large neutral amino acids - Mus musculus [Reaction:R-MMU-352107] SLC43A2 (LAT4)-mediated uptake of large neutral amino acids - Mus musculus [Reaction:R-MMU-352029] SLC6A12 (BGT-1)-mediated uptake of GABA and betaine - Mus musculus [Reaction:R-MMU-352059] SLC6A15-mediated amino acid uptake - Mus musculus [Reaction:R-MMU-352052] SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol - Mus musculus [Reaction:R-MMU-351987] SLC6A6-mediated uptake of taurine and beta-alanine - Mus musculus [Reaction:R-MMU-352232] SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol - Mus musculus [Reaction:R-MMU-352191] SLC7A8-mediated uptake of neutral amino acids - Mus musculus [Reaction:R-MMU-352364] SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine - Mus musculus [Reaction:R-MMU-352354] SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine - Mus musculus [Reaction:R-MMU-352347] SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine - Mus musculus [Reaction:R-MMU-352371] SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine - Mus musculus [Reaction:R-MMU-352379] SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane - Mus musculus [Reaction:R-MMU-352385] SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane - Mus musculus [Reaction:R-MMU-375417] SLC36A1-mediated uptake of glycine, proline, and alanine - Mus musculus [Reaction:R-MMU-375405] SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol - Mus musculus [Reaction:R-MMU-8870354] SLC36A4 transports extracellular L-Pro to the cytosol - Mus musculus [Reaction:R-MMU-375487] SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol - Mus musculus [Reaction:R-MMU-375473] SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol - Mus musculus [Reaction:R-MMU-375776] SLC7A1 (CAT-1)-mediated uptake of cationic amino acids - Mus musculus [Reaction:R-MMU-375770] SLC7A3 (CAT-3)-mediated uptake of cationic amino acids - Mus musculus [Reaction:R-MMU-376200] SLC7A10-mediated uptake of small neutral amino acids - Mus musculus [Reaction:R-MMU-378513] SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate - Mus musculus [Reaction:R-MMU-379426] SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine - Mus musculus [Reaction:R-MMU-379415] SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane - Mus musculus [Reaction:R-MMU-379432] SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu - Mus musculus [BlackBoxEvent:R-MMU-8959781] SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix - Mus musculus
inferredFrom	[Pathway:R-HSA-352230] Amino acid transport across the plasma membrane - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Amino acid transport across the plasma membrane
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-352230
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-9958863] SLC-mediated transport of amino acids
(inferredTo)	[Pathway:R-HSA-352230] Amino acid transport across the plasma membrane

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