Reactome | phospho-p-T210-PLK1 [cytosol]

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phospho-p-T210-PLK1 [cytosol] Show undefined attributes

catalystActivities	[CatalystActivity:9994490] protein serine/threonine kinase activity of p-T210-PLK1 [cytosol]
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-MMU-9851996] p-S43-FIRRM:p-T210-PLK1 [cytosol] - Mus musculus [Complex:R-MMU-2172193] p-T216,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP:p-T210-PLK1 [Golgi membrane] - Mus musculus [Complex:R-MMU-2314414] p-T216,S189,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP:p-T210-PLK1 [Golgi membrane] - Mus musculus
consumedByEvent	[Reaction:R-MMU-9853385] PPP1CC dephosphorylates PLK1 - Mus musculus [Reaction:R-MMU-9851946] FIRRM binds PLK1 - Mus musculus [Reaction:R-MMU-3002798] Cytosolic PLK1 translocates to the nucleus - Mus musculus [Reaction:R-MMU-8852324] GTSE1 binds PLK1 - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	9994489
displayName	phospho-p-T210-PLK1 [cytosol]
endCoordinate	603
hasModifiedResidue	[ModifiedResidue:9994477] O-phospho-L-threonine at 210 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-3000318] p-T210-PLK1 [cytosol] - Homo sapiens
maxDepth	1
name	phospho-p-T210-PLK1 Q07832
producedByEvent	[Reaction:R-MMU-3000327] PLK1 phosphorylates BORA - Mus musculus [Reaction:R-MMU-8852317] PLK1 phosphorylates GTSE1 - Mus musculus [Reaction:R-MMU-9853369] PLK1 phosphorylates FIRMM at S744 - Mus musculus
referenceEntity	[ReferenceGeneProduct:uniprot:Q07832] UniProt:Q07832
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48892] Mus musculus
stId	R-MMU-3000318
startCoordinate	1

Referrals

(activeUnit)	[CatalystActivity:10043926] protein serine/threonine kinase activity of p-T216,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP:p-T210-PLK1 [Golgi membrane] [CatalystActivity:10095192] protein serine/threonine kinase activity of FIRRM:p-T210-PLK1 [cytosol] [CatalystActivity:10047048] protein serine/threonine kinase activity of p-7S,2T-BORA:p-T210-PLK1 [cytosol] [CatalystActivity:10076151] protein serine/threonine kinase activity of GTSE1:p-T210-PLK1 [cytosol]
(hasComponent)	[Complex:R-MMU-2314414] p-T216,S189,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP:p-T210-PLK1 [Golgi membrane] [Complex:R-MMU-2172193] p-T216,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP:p-T210-PLK1 [Golgi membrane] [Complex:R-MMU-9851951] FIRRM:p-T210-PLK1 [cytosol] [Complex:R-MMU-9851996] p-S43-FIRRM:p-T210-PLK1 [cytosol] [Complex:R-MMU-8852323] GTSE1:p-T210-PLK1 [cytosol] [Complex:R-MMU-3000305] p-7S,2T-BORA:p-T210-PLK1 [cytosol]
(input)	[Reaction:R-MMU-9853385] PPP1CC dephosphorylates PLK1 [Reaction:R-MMU-9851946] FIRRM binds PLK1 [Reaction:R-MMU-3002798] Cytosolic PLK1 translocates to the nucleus [Reaction:R-MMU-8852324] GTSE1 binds PLK1
(output)	[Reaction:R-MMU-9853369] PLK1 phosphorylates FIRMM at S744 [Reaction:R-MMU-3000327] PLK1 phosphorylates BORA [Reaction:R-MMU-8852317] PLK1 phosphorylates GTSE1
(physicalEntity)	[CatalystActivity:9994490] protein serine/threonine kinase activity of p-T210-PLK1 [cytosol]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-3000318] p-T210-PLK1 [cytosol]

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