Reactome | HLCS biotinylates ACACA:Mn2+

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HLCS biotinylates ACACA:Mn2+ Show undefined attributes

catalystActivity	[CatalystActivity:10046772] biotin--[biotin carboxyl-carrier protein] ligase activity of HLCS [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10046824
displayName	HLCS biotinylates ACACA:Mn2+
eventOf	[Pathway:R-MMU-196780] Biotin transport and metabolism - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-2993814] HLCS biotinylates ACACA:Mn2+ - Homo sapiens
input	[Complex:R-MMU-2993826] ACACA:2Mn2+ [cytosol] [SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-199207] Btn [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	HLCS biotinylates ACACA:Mn2+
output	[SimpleEntity:R-ALL-76577] AMP [cytosol] [Complex:R-MMU-2993815] Btn-ACACA:2Mn2+ [cytosol] [SimpleEntity:R-ALL-111294] PPi [cytosol]
precedingEvent	[Reaction:R-MMU-199219] SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-2993814
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-196780] Biotin transport and metabolism
(inferredTo)	[Reaction:R-HSA-2993814] HLCS biotinylates ACACA:Mn2+

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