Reactome | Recruitment of Gab2 to PM and FCERI by binding to Grb2

Schema > Reaction > Entries

authored	[InstanceEdit:2871799] Niarakis, Anna, 2012-12-21
category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:2730834] Garapati, P V, 2012-12-05
dbId	2730846
displayName	Recruitment of Gab2 to PM and FCERI by binding to Grb2
edited	[InstanceEdit:2454233] Garapati, P V, 2012-08-22
input	[EntityWithAccessionedSequence:R-MMU-2685613] Gab2 [cytosol] [EntityWithAccessionedSequence:R-MMU-443287] Grb2 [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:2685226] The adapter molecule Gab2 regulates Fc epsilon RI-mediated signal transduction in mast cells [LiteratureReference:2685041] The limited contribution of Fyn and Gab2 to the high affinity IgE receptor signaling in mast cells [LiteratureReference:2685026] Scaffolding adapter Grb2-associated binder 2 requires Syk to transmit signals from FcepsilonRI
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Recruitment of Gab2 to PM and FCERI by binding to Grb2
orthologousEvent	[Reaction:R-HSA-2730848] Recruitment of GAB2 to PM and FCERI by binding to GRB2 - Homo sapiens
output	[Complex:R-MMU-2685680] Grb2:Gab2 [cytosol]
releaseDate	2013-06-11
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:3139040] Roncagalli, Romain, 2013-02-13
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-2730846
summation	[Summation:2685548] NTAL cooperates with LAT in mast cells to activate PI3K path...

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