Reactome | Grb2:Gab2 [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
consumedByEvent	[Reaction:R-MMU-2730869] Phosphorylation of Gab2 by Syk/Fyn - Mus musculus [BlackBoxEvent:R-MMU-9680646] Pik3r11:Pik3ca,b,d (Pi3k), Plcg2 (PLCgamma2), Grb2:Sos1, Shc1 (Shc), Ptpn11 (Shp2), Grb2:Gab2, Grb2:Gab3, Grap2 (MONA), Cbl:Grb2, Inpp5d (SHIP1), Inppl1 (SHIP2) bind p-8Y-Csf1r and are activated - Mus musculus
created	[InstanceEdit:2685710] Garapati, P V, 2012-12-03
dbId	2685680
displayName	Grb2:Gab2 [cytosol]
hasComponent	[EntityWithAccessionedSequence:R-MMU-2685613] Gab2 [cytosol] [EntityWithAccessionedSequence:R-MMU-443287] Grb2 [cytosol]
inDisease	false
isChimeric	false
literatureReference	[LiteratureReference:2685026] Scaffolding adapter Grb2-associated binder 2 requires Syk to transmit signals from FcepsilonRI
maxDepth	2
name	Grb2:Gab2
producedByEvent	[Reaction:R-MMU-2730846] Recruitment of Gab2 to PM and FCERI by binding to Grb2 - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-2685680

(input)	[BlackBoxEvent:R-MMU-9680646] Pik3r11:Pik3ca,b,d (Pi3k), Plcg2 (PLCgamma2), Grb2:Sos1, Shc1 (Shc), Ptpn11 (Shp2), Grb2:Gab2, Grb2:Gab3, Grap2 (MONA), Cbl:Grb2, Inpp5d (SHIP1), Inppl1 (SHIP2) bind p-8Y-Csf1r and are activated [Reaction:R-MMU-2730869] Phosphorylation of Gab2 by Syk/Fyn
(output)	[Reaction:R-MMU-2730846] Recruitment of Gab2 to PM and FCERI by binding to Grb2