Reactome | Proteasome mediated degradation of COP1

Schema > BlackBoxEvent > Entries

Proteasome mediated degradation of COP1 Show undefined attributes

catalystActivity	[CatalystActivity:9985423] endopeptidase activity of 26S proteasome [cytosol]
category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10007395
displayName	Proteasome mediated degradation of COP1
eventOf	[Pathway:R-MMU-349425] Autodegradation of the E3 ubiquitin ligase COP1 - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-264458] Proteasome mediated degradation of COP1 - Homo sapiens
input	[Complex:R-MMU-349433] ubiquitinated phospho-COP1(ser-387) [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Proteasome mediated degradation of COP1
output	4 × [DefinedSet:R-MMU-113595] Ub [cytosol]
precedingEvent	[Reaction:R-MMU-264444] Autoubiquitination of phospho-COP1(Ser-387 ) - Mus musculus
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:48892] Mus musculus
stId	R-MMU-264458
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-349425] Autodegradation of the E3 ubiquitin ligase COP1
(inferredTo)	[BlackBoxEvent:R-HSA-264458] Proteasome mediated degradation of COP1

Cite Us!