Reactome | Activation of the phototransduction cascade

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Activation of the phototransduction cascade Show undefined attributes

created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10098679
displayName	Activation of the phototransduction cascade
eventOf	[Pathway:R-MMU-2514856] The phototransduction cascade - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:21771] G protein-coupled opsin signaling pathway
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-MMU-74101] Photons induce isomerization of 11c-retinyl to at-retinyl - Mus musculus [Reaction:R-MMU-2485182] Gt-GTP dissociates to GNAT1-GTP and GNB1:GNGT1 - Mus musculus [Reaction:R-MMU-74059] PDE6 hydrolyses cGMP to GMP - Mus musculus [Reaction:R-MMU-2514867] cGMP:CNG transports Na+ and Ca2+ into the rod outer segment - Mus musculus [Reaction:R-MMU-2514865] cGMP dissociates from CNG channels - Mus musculus
inferredFrom	[Pathway:R-HSA-2485179] Activation of the phototransduction cascade - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Activation of the phototransduction cascade
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-2485179
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-2514856] The phototransduction cascade
(inferredTo)	[Pathway:R-HSA-2485179] Activation of the phototransduction cascade

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