Reactome | Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1)

Schema > Reaction > Entries

Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10041960
displayName	Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1)
eventOf	[Pathway:R-MMU-195253] Degradation of beta-catenin by the destruction complex - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-MMU-2130282] Degradation of ubiquitinated beta catenin by the proteasome - Mus musculus
inferredFrom	[Reaction:R-HSA-2130286] Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) - Homo sapiens
input	[Complex:R-MMU-2130280] RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] 4 × [DefinedSet:R-MMU-113595] Ub [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1)
output	[Complex:R-MMU-2130284] ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol]
precedingEvent	[Reaction:R-MMU-2130279] Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-2130286
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-195253] Degradation of beta-catenin by the destruction complex
(precedingEvent)	[BlackBoxEvent:R-MMU-2130282] Degradation of ubiquitinated beta catenin by the proteasome
(inferredTo)	[Reaction:R-HSA-2130286] Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1)

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