Reactome | Eicosanoids

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Eicosanoids Show undefined attributes

compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:17957] endoplasmic reticulum lumen [Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10098797
displayName	Eicosanoids
eventOf	[Pathway:R-MMU-211897] Cytochrome P450 - arranged by substrate type - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:9963] icosanoid metabolic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-MMU-211873] CYP4F2, 4F3 20-hydroxylate LTB4 - Mus musculus [Reaction:R-MMU-215526] CYP4F3 20-hydroxylates LTB4 - Mus musculus [Reaction:R-MMU-211919] CYP4F8 19-hydroxylates PGH2 - Mus musculus [Reaction:R-MMU-76500] TBXAS1 isomerises PGH2 to TXA2 - Mus musculus [Reaction:R-MMU-76496] PTGIS, CYP8A1 isomerise PGH2 to PGI2 - Mus musculus [Reaction:R-MMU-5602295] CYP4F22 20-hydroxylates TrXA3 - Mus musculus
inferredFrom	[Pathway:R-HSA-211979] Eicosanoids - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Eicosanoids
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-211979
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-211897] Cytochrome P450 - arranged by substrate type
(inferredTo)	[Pathway:R-HSA-211979] Eicosanoids