Reactome | Duplex miRNA is loaded into Argonaute

Schema > BlackBoxEvent > Entries

category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10041870
displayName	Duplex miRNA is loaded into Argonaute
eventOf	[Pathway:R-MMU-203927] MicroRNA (miRNA) biogenesis - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-MMU-210805] Removal of miRNA passenger strand - Mus musculus
inferredFrom	[BlackBoxEvent:R-HSA-2106614] Duplex miRNA is loaded into Argonaute - Homo sapiens
input	[DefinedSet:R-MMU-6789248] TARBP2,PRKRA RLC:duplex miRNA [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Duplex miRNA is loaded into Argonaute
output	[DefinedSet:R-MMU-6789253] TARBP2,PRKRA:DICER1:Pre-RISC (miRNA) [cytosol]
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:48892] Mus musculus
stId	R-MMU-2106614
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-MMU-203927] MicroRNA (miRNA) biogenesis
(precedingEvent)	[BlackBoxEvent:R-MMU-210805] Removal of miRNA passenger strand
(inferredTo)	[BlackBoxEvent:R-HSA-2106614] Duplex miRNA is loaded into Argonaute

Cite Us!