Reactome | YAP1- and WWTR1 (TAZ)-stimulated gene expression

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YAP1- and WWTR1 (TAZ)-stimulated gene expression Show undefined attributes

compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10100859
displayName	YAP1- and WWTR1 (TAZ)-stimulated gene expression
eventOf	[Pathway:R-MMU-212436] Generic Transcription Pathway - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:17841] transcription initiation at RNA polymerase II promoter
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-MMU-2032781] WWTR1 (TAZ) binds TEAD - Mus musculus [Reaction:R-MMU-2032775] YAP1 binds TEAD1 - Mus musculus [Reaction:R-MMU-8871260] YAP1 binds TEAD2 - Mus musculus [Reaction:R-MMU-8871266] YAP1 binds TEAD3 - Mus musculus [Reaction:R-MMU-8871265] YAP1 binds TEAD4 - Mus musculus [Reaction:R-MMU-2032794] WWTR1 (TAZ), TBX5, and PCAF form a complex - Mus musculus
inferredFrom	[Pathway:R-HSA-2032785] YAP1- and WWTR1 (TAZ)-stimulated gene expression - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	YAP1- and WWTR1 (TAZ)-stimulated gene expression
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-2032785
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-212436] Generic Transcription Pathway
(hasEncapsulatedEvent)	[Pathway:R-MMU-1236394] Signaling by ERBB4 [Pathway:R-MMU-2028269] Signaling by Hippo
(inferredTo)	[Pathway:R-HSA-2032785] YAP1- and WWTR1 (TAZ)-stimulated gene expression

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