Reactome | PDK1:PIP2,PIP3 [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10004387] protein serine/threonine kinase activity of PDK1:PIP2,PIP3 [plasma membrane]
compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-MMU-202349] CARMA1 bound to PDK1 [plasma membrane] - Mus musculus [Complex:R-MMU-202445] CARMA1 trimer [plasma membrane] - Mus musculus
consumedByEvent	[Reaction:R-MMU-202394] Translocation of CARMA1 to Plasma membrane - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10004207
displayName	PDK1:PIP2,PIP3 [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-MMU-61459] PDPK1 [plasma membrane] [DefinedSet:R-ALL-202277] PIP3, PI(3,4)P2 [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-202311] PDK1:PIP2,PIP3 [plasma membrane] - Homo sapiens
maxDepth	3
name	PDK1:PIP2,PIP3
producedByEvent	[Reaction:R-MMU-202164] Translocation of PDK1 to Plasma membrane - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-202311
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-MMU-202394] Translocation of CARMA1 to Plasma membrane
(physicalEntity)	[CatalystActivity:10004387] protein serine/threonine kinase activity of PDK1:PIP2,PIP3 [plasma membrane]
(hasComponent)	[Complex:R-MMU-202349] CARMA1 bound to PDK1 [plasma membrane] [Complex:R-MMU-202440] Activated CARMA1 [plasma membrane] [Complex:R-MMU-202445] CARMA1 trimer [plasma membrane]
(output)	[Reaction:R-MMU-202164] Translocation of PDK1 to Plasma membrane
(inferredTo)	[Complex:R-HSA-202311] PDK1:PIP2,PIP3 [plasma membrane]