Reactome | Active NTRK1 binds IRS1/2

Schema > Reaction > Entries

category	binding
compartment	[Compartment:947587] cytoplasmic side of plasma membrane
created	[InstanceEdit:198310] 2007-07-10 08:01:55
dbId	198275
displayName	Active NTRK1 binds IRS1/2
input	[Complex:R-MMU-198286] Activated NTRK-1 [plasma membrane] [DefinedSet:R-MMU-198304] Irs1,2 [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:198308] IRS-1 and IRS-2 are recruited by TrkA receptor and oncogenic TRK-T1
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Active NTRK1 binds IRS1/2
orthologousEvent	[Reaction:R-HSA-198211] Active TRKA binds IRS1/2 - Homo sapiens
output	[Complex:R-MMU-198287] Activated NTRK-1:IRS1/2 [plasma membrane]
releaseDate	2005-09-26
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:202668] Greene, LA, 2007-11-08 15:39:37
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-198275
summation	[Summation:198210] IRS1 and IRS2 bind directly to TRK receptors phosphorylated ...

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