Reactome | c-src associates with Cx43 in gap junctions

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c-src associates with Cx43 in gap junctions Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10001062
displayName	c-src associates with Cx43 in gap junctions
eventOf	[Pathway:R-MMU-191650] Regulation of gap junction activity - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-191636] Phosphorylation of Cx43 by c-src - Mus musculus
inferredFrom	[Reaction:R-HSA-191654] c-src associates with Cx43 in gap junctions - Homo sapiens
input	[Complex:R-MMU-191652] Cx43 :ZO-1 gap junction [plasma membrane] 12 × [EntityWithAccessionedSequence:R-MMU-191648] SRC-2 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	c-src associates with Cx43 in gap junctions
output	[Complex:R-MMU-191653] Cx43:ZO-1:c-src gap junction [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-191654
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-191650] Regulation of gap junction activity
(precedingEvent)	[Reaction:R-MMU-191636] Phosphorylation of Cx43 by c-src
(inferredTo)	[Reaction:R-HSA-191654] c-src associates with Cx43 in gap junctions

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