Reactome | FGF10 activates Ptf1 expression in early pancreatic buds

Schema > BlackBoxEvent > Entries

authored	[InstanceEdit:351500] Ferrer, J, Tello-Ruiz, MK, 2008-05-23
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:190102] Tello-Ruiz, MK, 2006-12-18 05:46:40
dbId	190093
displayName	FGF10 activates Ptf1 expression in early pancreatic buds
edited	[InstanceEdit:190295] Tello-Ruiz, MK, 2006-12-19 19:02:30
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:190094] An endothelial-mesenchymal relay pathway regulates early phases of pancreas development
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	FGF10 activates Ptf1 expression in early pancreatic buds
orthologousEvent	[BlackBoxEvent:R-HSA-210788] HNF1B- and FGF10-dependent synthesis of PTF1A protein - Homo sapiens
output	[EntityWithAccessionedSequence:R-MMU-190090] ptf1a [nucleoplasm]
regulatedBy	[PositiveRegulation:R-MMU-190299] Positive regulation by 'fgf10 [extracellular region]'
releaseDate	2008-06-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:349683] Jensen, J, 2008-05-12 21:46:53
schemaClass	BlackBoxEvent
species	[Species:48892] Mus musculus
stId	R-MMU-190093
summation	[Summation:190097] Fgf10-/- embryos have markedly reduced Ptf1 mRNA expression ...

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