Reactome | HNF1B- and FGF10-dependent synthesis of PTF1A protein

Schema > BlackBoxEvent > Entries

HNF1B- and FGF10-dependent synthesis of PTF1A protein Show undefined attributes

authored	[InstanceEdit:351500] Ferrer, J, Tello-Ruiz, MK, 2008-05-23
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:210768] D'Eustachio, P, 2008-01-15 23:30:34
dbId	210788
displayName	HNF1B- and FGF10-dependent synthesis of PTF1A protein
edited	[InstanceEdit:349681] D'Eustachio, P, 2008-05-12 21:43:33
eventOf	[Pathway:R-HSA-210747] Regulation of gene expression in early pancreatic precursor cells - Homo sapiens
inferredFrom	[BlackBoxEvent:R-MMU-190093] FGF10 activates Ptf1 expression in early pancreatic buds - Mus musculus [BlackBoxEvent:R-MMU-187247] HNF1b transactivates Ptf1a - Mus musculus
input	[EntityWithAccessionedSequence:R-HSA-9606080] PTF1A gene [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	HNF1B- and FGF10-dependent synthesis of PTF1A protein
output	[EntityWithAccessionedSequence:R-HSA-210783] PTF1A [nucleoplasm]
regulatedBy	[PositiveGeneExpressionRegulation:R-HSA-210759] Positive gene expression regulation by 'FGF10 [extracellular region]' [PositiveGeneExpressionRegulation:R-HSA-210776] Positive gene expression regulation by 'HNF1B [nucleoplasm]'
releaseDate	2008-06-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:349683] Jensen, J, 2008-05-12 21:46:53
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-210788
summation	[Summation:210786] The PTF1A gene is transcribed, its mRNA is translated, and t...
updateTrackers	[UpdateTracker:9787544] Update Tracker - [BlackBoxEvent:210788] HNF1B- and FGF10-dependent synthesis of PTF1A protein - v44:[add_removeRegulator] [UpdateTracker:9779305] Update Tracker - [BlackBoxEvent:210788] HNF1B- and FGF10-dependent synthesis of PTF1A protein - v65:[addInput]

Referrals

(updatedInstance)	[UpdateTracker:9787544] Update Tracker - [BlackBoxEvent:210788] HNF1B- and FGF10-dependent synthesis of PTF1A protein - v44:[add_removeRegulator] [UpdateTracker:9779305] Update Tracker - [BlackBoxEvent:210788] HNF1B- and FGF10-dependent synthesis of PTF1A protein - v65:[addInput]
(hasEvent)	[Pathway:R-HSA-210747] Regulation of gene expression in early pancreatic precursor cells
(inferredTo)	[BlackBoxEvent:R-MMU-190093] FGF10 activates Ptf1 expression in early pancreatic buds [BlackBoxEvent:R-MMU-187247] HNF1b transactivates Ptf1a