Reactome | phospho-Rb1 [nucleoplasm]

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phospho-Rb1 [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-MMU-113503] PP2A mediated localization of RB1 protein in chromatin - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	9992758
displayName	phospho-Rb1 [nucleoplasm]
endCoordinate	928
hasModifiedResidue	[ModifiedResidue:9985676] O-phospho-L-serine at 795 (in Homo sapiens) [ModifiedResidue:9985655] O-phospho-L-serine at 230 (in Homo sapiens) [ModifiedResidue:9985658] O-phospho-L-serine at 249 (in Homo sapiens) [ModifiedResidue:9985661] O-phospho-L-threonine at 252 (in Homo sapiens) [ModifiedResidue:9985664] O-phospho-L-serine at 608 (in Homo sapiens) [ModifiedResidue:9985667] O-phospho-L-serine at 612 (in Homo sapiens) [ModifiedResidue:9985670] O-phospho-L-serine at 780 (in Homo sapiens) [ModifiedResidue:9985673] O-phospho-L-serine at 788 (in Homo sapiens) [ModifiedResidue:9985679] O-phospho-L-serine at 807 (in Homo sapiens) [ModifiedResidue:9985682] O-phospho-L-serine at 811 (in Homo sapiens) [ModifiedResidue:9985685] O-phospho-L-threonine at 356 (in Homo sapiens) [ModifiedResidue:9985688] O-phospho-L-threonine at 373 (in Homo sapiens) [ModifiedResidue:9985691] O-phospho-L-threonine at 821 (in Homo sapiens) [ModifiedResidue:9985694] O-phospho-L-threonine at 826 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-188389] hyperphosphorylated RB1 [nucleoplasm] - Homo sapiens
maxDepth	1
memberOf	[DefinedSet:R-MMU-187920] p-FZR1,p-RB1 [nucleoplasm] - Mus musculus
name	phospho-Rb1 hyperphosphorylated RB1 P13405
producedByEvent	[Reaction:R-MMU-188390] Cyclin E:CDK2-mediated phosphorylation of RB1 - Mus musculus [Reaction:R-MMU-188390] Cyclin E:CDK2-mediated phosphorylation of RB1 - Mus musculus [Reaction:R-MMU-188390] Cyclin E:CDK2-mediated phosphorylation of RB1 - Mus musculus [Reaction:R-MMU-188390] Cyclin E:CDK2-mediated phosphorylation of RB1 - Mus musculus [Reaction:R-MMU-188390] Cyclin E:CDK2-mediated phosphorylation of RB1 - Mus musculus [Reaction:R-MMU-188390] Cyclin E:CDK2-mediated phosphorylation of RB1 - Mus musculus [Reaction:R-MMU-188390] Cyclin E:CDK2-mediated phosphorylation of RB1 - Mus musculus [Reaction:R-MMU-188390] Cyclin E:CDK2-mediated phosphorylation of RB1 - Mus musculus [Reaction:R-MMU-188390] Cyclin E:CDK2-mediated phosphorylation of RB1 - Mus musculus [Reaction:R-MMU-188390] Cyclin E:CDK2-mediated phosphorylation of RB1 - Mus musculus [Reaction:R-MMU-188390] Cyclin E:CDK2-mediated phosphorylation of RB1 - Mus musculus [Reaction:R-MMU-188390] Cyclin E:CDK2-mediated phosphorylation of RB1 - Mus musculus [Reaction:R-MMU-188390] Cyclin E:CDK2-mediated phosphorylation of RB1 - Mus musculus [Reaction:R-MMU-188390] Cyclin E:CDK2-mediated phosphorylation of RB1 - Mus musculus
referenceEntity	[ReferenceGeneProduct:uniprot:P13405] UniProt:P13405 Rb1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48892] Mus musculus
stId	R-MMU-188389
startCoordinate	2

Referrals

(hasMember)	[DefinedSet:R-MMU-187920] p-FZR1,p-RB1 [nucleoplasm]
(input)	[Reaction:R-MMU-113503] PP2A mediated localization of RB1 protein in chromatin
(output)	[Reaction:R-MMU-188390] Cyclin E:CDK2-mediated phosphorylation of RB1
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-188389] hyperphosphorylated RB1 [nucleoplasm]

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