Reactome | 1/3-PP-IP5 transports from the cytosol to the nucleus

Schema > Reaction > Entries

1/3-PP-IP5 transports from the cytosol to the nucleus Show undefined attributes

catalystActivity	[CatalystActivity:10036609] narrow pore channel activity of Nuclear Pore Complex (NPC) [nuclear envelope]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10036791
displayName	1/3-PP-IP5 transports from the cytosol to the nucleus
eventOf	[Pathway:R-MMU-1855229] IP6 and IP7 transport between cytosol and nucleus - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-1855157] 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus - Mus musculus
goBiologicalProcess	[GO_BiologicalProcess:160267] import into nucleus
inferredFrom	[Reaction:R-HSA-1855212] 1/3-PP-IP5 transports from the cytosol to the nucleus - Homo sapiens
input	[DefinedSet:R-ALL-2023974] 1/3-PP-IP5 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	1/3-PP-IP5 transports from the cytosol to the nucleus
output	[DefinedSet:R-ALL-2023944] 1/3-PP-IP5 [nucleoplasm]
precedingEvent	[Reaction:R-MMU-1855216] IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol - Mus musculus [Reaction:R-MMU-2023973] (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-1855212
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-1855229] IP6 and IP7 transport between cytosol and nucleus
(precedingEvent)	[Reaction:R-MMU-1855157] 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus
(inferredTo)	[Reaction:R-HSA-1855212] 1/3-PP-IP5 transports from the cytosol to the nucleus

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