Reactome | Free APC/C phosphorylated by Cyclin B:Cdc2

Schema > Reaction > Entries

Free APC/C phosphorylated by Cyclin B:Cdc2 Show undefined attributes

catalystActivity	[CatalystActivity:9998617] cyclin-dependent protein serine/threonine kinase activity of CCNB1:p-T161-CDK1 [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	9998632
displayName	Free APC/C phosphorylated by Cyclin B:Cdc2
eventOf	[Pathway:R-MMU-176412] Phosphorylation of the APC/C - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-174132] Free APC/C phosphorylated by Cyclin B:Cdc2 - Homo sapiens
input	[Complex:R-MMU-174109] phosphorylated anaphase promoting complex (APC/C) [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Free APC/C phosphorylated by Cyclin B:Cdc2
output	[Complex:R-MMU-174109] phosphorylated anaphase promoting complex (APC/C) [nucleoplasm]
precedingEvent	[Reaction:R-MMU-170153] Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-174132
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-176412] Phosphorylation of the APC/C
(inferredTo)	[Reaction:R-HSA-174132] Free APC/C phosphorylated by Cyclin B:Cdc2

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