Reactome | p-2S-SMAD2,3:SMAD4 [cytosol]

Schema > DefinedSet > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-MMU-2031357] WWTR1:p-2S-SMAD2,3:SMAD4 [cytosol] - Mus musculus
consumedByEvent	[Reaction:R-MMU-2031355] WWTR1 binds SMAD2/3:SMAD4 heterotrimer - Mus musculus [BlackBoxEvent:R-MMU-173488] The SMAD2/3:SMAD4 complex transfers to the nucleus - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	9997509
displayName	p-2S-SMAD2,3:SMAD4 [cytosol]
hasMember	[Complex:R-MMU-206866] p-2S-SMAD2:p-2S-SMAD2:SMAD4 [cytosol] - Mus musculus [Complex:R-MMU-9736926] p-2S-SMAD2:p-2S-SMAD3:SMAD4 [cytosol] - Mus musculus [Complex:R-MMU-9736931] p-2S-SMAD3:p-2S-SMAD3:SMAD4 [cytosol] - Mus musculus
inDisease	false
inferredFrom	[DefinedSet:R-HSA-171175] p-2S-SMAD2,3:SMAD4 [cytosol] - Homo sapiens
maxDepth	3
name	p-2S-SMAD2,3:SMAD4 Phospho-R-SMAD:CO-SMAD complex
producedByEvent	[Reaction:R-MMU-170847] Phosphorylated SMAD2 and SMAD3 form a complex with SMAD4 - Mus musculus
schemaClass	DefinedSet
species	[Species:48892] Mus musculus
stId	R-MMU-171175

(input)	[Reaction:R-MMU-2031355] WWTR1 binds SMAD2/3:SMAD4 heterotrimer [BlackBoxEvent:R-MMU-173488] The SMAD2/3:SMAD4 complex transfers to the nucleus
(hasComponent)	[Complex:R-MMU-2031357] WWTR1:p-2S-SMAD2,3:SMAD4 [cytosol]
(output)	[Reaction:R-MMU-170847] Phosphorylated SMAD2 and SMAD3 form a complex with SMAD4
(inferredTo)	[DefinedSet:R-HSA-171175] p-2S-SMAD2,3:SMAD4 [cytosol]

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