Reactome | PLCG1 [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-MMU-5654166] activated FGFR4:PLCG1 [plasma membrane] - Mus musculus [Complex:R-MMU-9699982] Active ALK:PLCG1 [plasma membrane] - Mus musculus
consumedByEvent	[Reaction:R-MMU-5654167] Activated FGFR1 binds PLCG1 - Mus musculus [Reaction:R-MMU-9700149] Active ALK binds PLCG1 - Mus musculus [Reaction:R-MMU-5654163] Activated FGFR4 binds PLCG1 - Mus musculus [Reaction:R-MMU-5654159] Activated FGFR2 binds PLCG1 - Mus musculus [Reaction:R-MMU-5654224] Activated FGFR3 binds PLCG1 - Mus musculus [Reaction:R-MMU-186765] PLC-gamma binds to the active receptor - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10000138
displayName	PLCG1 [plasma membrane]
endCoordinate	1290
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-167682] PLCG1 [plasma membrane] - Homo sapiens
maxDepth	1
name	PLCG1 Q62077
referenceEntity	[ReferenceGeneProduct:uniprot:Q62077] UniProt:Q62077 Plcg1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48892] Mus musculus
stId	R-MMU-167682
startCoordinate	2

(input)	[Reaction:R-MMU-9700149] Active ALK binds PLCG1 [Reaction:R-MMU-5654163] Activated FGFR4 binds PLCG1 [Reaction:R-MMU-5654159] Activated FGFR2 binds PLCG1 [Reaction:R-MMU-5654167] Activated FGFR1 binds PLCG1 [Reaction:R-MMU-5654224] Activated FGFR3 binds PLCG1 [Reaction:R-MMU-186765] PLC-gamma binds to the active receptor
(hasComponent)	[Complex:R-MMU-9699982] Active ALK:PLCG1 [plasma membrane] [Complex:R-MMU-2023858] PLCG1:Ca2+ [plasma membrane] [Complex:R-MMU-5654166] activated FGFR4:PLCG1 [plasma membrane] [Complex:R-MMU-5654162] activated FGFR2:PLCG1 [plasma membrane] [Complex:R-MMU-5654155] activated FGFR1:PLCG1 [plasma membrane] [Complex:R-MMU-5654226] activated FGFR3:PLCG1 [plasma membrane] [Complex:R-MMU-186795] PDGF:Phospho-PDGF receptor dimer:PLC-gamma [plasma membrane]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-167682] PLCG1 [plasma membrane]