Reactome | Enzyme-bound ATP is released

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Enzyme-bound ATP is released Show undefined attributes

catalystActivity	[CatalystActivity:9996184] proton transmembrane transporter activity of ATPase:ATP [mitochondrial inner membrane]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	9996186
displayName	Enzyme-bound ATP is released
eventOf	[Pathway:R-MMU-163210] Formation of ATP by chemiosmotic coupling - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-5672027] ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane - Mus musculus [Reaction:R-MMU-163215] SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane - Mus musculus [Reaction:R-MMU-164840] ADP and Pi bind to ATPase - Mus musculus
goBiologicalProcess	[GO_BiologicalProcess:81447] proton motive force-driven mitochondrial ATP synthesis
inferredFrom	[Reaction:R-HSA-164834] Enzyme-bound ATP is released - Homo sapiens
input	[Complex:R-MMU-164835] ATPase:ATP [mitochondrial inner membrane] 3 × [SimpleEntity:R-ALL-163953] H+ [mitochondrial intermembrane space]
isInDisease	false
isInferred	true
maxDepth	1
name	Enzyme-bound ATP is released
output	[SimpleEntity:R-ALL-113593] ATP [mitochondrial matrix] [Complex:R-MMU-74186] F1Fo ATP synthase [mitochondrial inner membrane] 3 × [SimpleEntity:R-ALL-113529] H+ [mitochondrial matrix]
precedingEvent	[Reaction:R-MMU-164832] ATPase synthesizes ATP - Mus musculus [Reaction:R-MMU-163217] Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 - Mus musculus [Reaction:R-MMU-164651] Electron transfer from ubiquinol to cytochrome c of complex III - Mus musculus [Reaction:R-MMU-163214] Electron transfer from reduced cytochrome c to molecular oxygen - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-164834
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(precedingEvent)	[Reaction:R-MMU-5672027] ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane [Reaction:R-MMU-163215] SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane [Reaction:R-MMU-164840] ADP and Pi bind to ATPase
(hasEvent)	[Pathway:R-MMU-163210] Formation of ATP by chemiosmotic coupling
(inferredTo)	[Reaction:R-HSA-164834] Enzyme-bound ATP is released

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