Reactome | GRB2:p-SHP2:p-KIT complex [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-MMU-1562560] p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] - Mus musculus [Complex:R-MMU-1433545] GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] - Mus musculus
consumedByEvent	[Reaction:R-MMU-205234] Indirect recruitment of GAB2 to p-KIT - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10005984
displayName	GRB2:p-SHP2:p-KIT complex [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-MMU-74686] Grb2 [cytosol] [Complex:R-MMU-1433530] p-SHP2:p-KIT complex [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-1433549] GRB2:p-SHP2:p-KIT complex [plasma membrane] - Homo sapiens
maxDepth	6
name	GRB2:p-SHP2:p-KIT complex
producedByEvent	[Reaction:R-MMU-1433428] GRB2 is indirectly recruited to p-KIT through SHP2 - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-1433549
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-MMU-205234] Indirect recruitment of GAB2 to p-KIT
(hasComponent)	[Complex:R-MMU-1433545] GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] [Complex:R-MMU-1562560] p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] [Complex:R-MMU-1562561] PI3K:p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane]
(output)	[Reaction:R-MMU-1433428] GRB2 is indirectly recruited to p-KIT through SHP2
(inferredTo)	[Complex:R-HSA-1433549] GRB2:p-SHP2:p-KIT complex [plasma membrane]