Reactome | Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:SHP2 [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10028597] protein tyrosine phosphatase activity of Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:SHP2 [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-MMU-1169192] PTP1B dephosphorylates GHR - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10028455
displayName	Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:SHP2 [plasma membrane]
hasComponent	[Complex:R-MMU-1168898] Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer [plasma membrane] [EntityWithAccessionedSequence:R-MMU-210625] PTPN1 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-1169227] Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:SHP2 [plasma membrane] - Homo sapiens
maxDepth	5
name	Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:SHP2
producedByEvent	[Reaction:R-MMU-1168445] PTP1B binds the GH receptor complex - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-1169227
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-MMU-1169192] PTP1B dephosphorylates GHR
(physicalEntity)	[CatalystActivity:10028597] protein tyrosine phosphatase activity of Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:SHP2 [plasma membrane]
(output)	[Reaction:R-MMU-1168445] PTP1B binds the GH receptor complex
(inferredTo)	[Complex:R-HSA-1169227] Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:SHP2 [plasma membrane]

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