Reactome | (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C)

Schema > Reaction > Entries

(d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) Show undefined attributes

catalystActivity	[CatalystActivity:9991205] 5'-nucleotidase activity of NT5C dimer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	9991207
displayName	(d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C)
eventOf	[Pathway:R-MMU-74259] Purine catabolism - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-109470] (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) - Homo sapiens
input	[DefinedSet:R-ALL-500120] (d)GMP, (d)IMP [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	(d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) GMP + H2O => guanosine + phosphate dGMP + H2O => 2'-deoxyguanosine + phosphate IMP + H2O => inosine + phosphate dIMP + H2O => 2'-deoxyinosine + phosphate
output	[DefinedSet:R-ALL-500118] Gu-Rib, dG, Ino, dI [cytosol] [SimpleEntity:R-ALL-29372] Pi [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-109470
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-74259] Purine catabolism
(inferredTo)	[Reaction:R-HSA-109470] (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C)

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