Reactome | CDH1,CDH11 promote stabilization of IL6ST protein

Schema > BlackBoxEvent > Entries

authored	[InstanceEdit:9968599] Orlic-Milacic, Marija, 2025-10-17
category	uncertain
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9968599] Orlic-Milacic, Marija, 2025-10-17
dbId	9968598
displayName	CDH1,CDH11 promote stabilization of IL6ST protein
edited	[InstanceEdit:9984139] Orlic-Milacic, Marija, 2026-03-03
eventOf	[Pathway:R-HSA-9958825] Activation of STAT3 by cadherin engagement - Homo sapiens
inferredFrom	[BlackBoxEvent:R-MMU-9968619] Il6st protein stabilization by Cdh1,Cdh11 - Mus musculus
input	[EntityWithAccessionedSequence:R-HSA-448453] IL6ST [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9984518] Orlic-Milacic, Marija, 2026-03-09
name	CDH1,CDH11 promote stabilization of IL6ST protein
regulatedBy	[NegativeRegulation:9959462] Negative regulation by 'Engaged CDH1,(CDH11) [plasma membrane]'
releaseDate	2026-03-25
releaseStatus	NEW
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9975417] Raptis, Leda, 2025-11-21
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9968598
summation	[Summation:9968617] CDH1 (del Valle et al. 2013: recombinant CDH1 of unspecified...

(hasEvent)	[Pathway:R-HSA-9958825] Activation of STAT3 by cadherin engagement
(inferredTo)	[BlackBoxEvent:R-MMU-9968619] Il6st protein stabilization by Cdh1,Cdh11

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