Reactome | S-farn-C589-GBP1 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

S-farn-C589-GBP1 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-9956689] GBP1:G-actin [cytosol] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9956706] GBP1 binds actin - Homo sapiens [Reaction:R-HSA-9954237] PIM1 phosphorylates GBP1 - Homo sapiens [Reaction:R-HSA-9968553] GBP1 binds GTP - Homo sapiens
created	[InstanceEdit:9947847] Shamovsky, Veronica, 2025-05-14
dbId	9947912
displayName	S-farn-C589-GBP1 [cytosol]
endCoordinate	592
hasModifiedResidue	[GroupModifiedResidue:9947933] S-farnesyl-L-cysteine (farnesyl group) at 589
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-RNO-9947912] Gbp1 [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-RNO-9947912-2] Gbp3 [cytosol] - Rattus norvegicus [DefinedSet:R-RNO-9947912-3] Homologues of S-farn-C589-GBP1 [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-9947912] GBP1 [cytosol] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-9947912] GBP1 [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-BTA-9947912-2] S-farn-C589-GBP1 [cytosol] - Bos taurus [DefinedSet:R-BTA-9947912-3] Homologues of S-farn-C589-GBP1 [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-SSC-9947912] GBP1 [cytosol] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-9947912] si:ch211-209n20.1 [cytosol] - Danio rerio [EntityWithAccessionedSequence:R-DRE-9947912-2] gbp2 [cytosol] - Danio rerio [EntityWithAccessionedSequence:R-DRE-9947912-3] S-farn-C589-GBP1 [cytosol] - Danio rerio [EntityWithAccessionedSequence:R-DRE-9947912-4] gbp1 [cytosol] - Danio rerio [DefinedSet:R-DRE-9947912-5] Homologues of S-farn-C589-GBP1 [cytosol] - Danio rerio [EntityWithAccessionedSequence:R-XTR-9947912] gbp7 [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-XTR-9947912-2] gbp6.2 [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-XTR-9947912-3] gbp1 [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-XTR-9947912-4] gbp4 [cytosol] - Xenopus tropicalis [DefinedSet:R-XTR-9947912-5] Homologues of S-farn-C589-GBP1 [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-9947912] GBP1 [cytosol] - Gallus gallus [EntityWithAccessionedSequence:R-GGA-9947912-2] S-farn-C589-GBP1 [cytosol] - Gallus gallus [EntityWithAccessionedSequence:R-GGA-9947912-3] LOC121106469 [cytosol] - Gallus gallus [EntityWithAccessionedSequence:R-GGA-9947912-4] LOC121106627 [cytosol] - Gallus gallus [EntityWithAccessionedSequence:R-GGA-9947912-5] LOC121106626 [cytosol] - Gallus gallus [DefinedSet:R-GGA-9947912-6] Homologues of S-farn-C589-GBP1 [cytosol] - Gallus gallus [EntityWithAccessionedSequence:R-DDI-9947912] S-farn-C589-GBP1 [cytosol] - Dictyostelium discoideum
maxDepth	1
modified	[InstanceEdit:9954294] Shamovsky, Veronica, 2025-06-06
name	S-farn-C589-GBP1 Interferon-induced guanylate-binding protein 1 GBP1_HUMAN
producedByEvent	[Reaction:R-HSA-9948016] FNTA:FNTB transfers farnesyl to GBP1 - Homo sapiens [Reaction:R-HSA-9953173] GMP dissociates from the GBP1 oligomer - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:P32455] UniProt:P32455 GBP1
referenceType	ReferenceGeneProduct
repeatedUnitOf	[Polymer:R-HSA-9947869] GBP1 oligomer [cytosol] - Homo sapiens
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9947912
startCoordinate	1

Referrals

(input)	[Reaction:R-HSA-9954237] PIM1 phosphorylates GBP1 [Reaction:R-HSA-9956706] GBP1 binds actin [Reaction:R-HSA-9968553] GBP1 binds GTP
(hasComponent)	[Complex:R-HSA-9956689] GBP1:G-actin [cytosol] [Complex:R-HSA-9947884] S-farn-GBP1:GTP [cytosol]
(output)	[Reaction:R-HSA-9953173] GMP dissociates from the GBP1 oligomer [Reaction:R-HSA-9948016] FNTA:FNTB transfers farnesyl to GBP1
(repeatedUnit)	[Polymer:R-HSA-9947869] GBP1 oligomer [cytosol]

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