Reactome | Dengue virion:HAVCR1 induces autophagosome formation

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Dengue virion:HAVCR1 induces autophagosome formation Show undefined attributes

authored	[InstanceEdit:9945844] Stephan, Ralf, 2025-04-19
category	uncertain
compartment	[Compartment:5683628] autophagosome membrane [Compartment:74700] endosome membrane
created	[InstanceEdit:9945933] Stephan, Ralf, 2025-04-20
crossReference	[DatabaseIdentifier:12020825] Mondo:0005502
dbId	9945936
disease	[Disease:3244610] dengue disease
displayName	Dengue virion:HAVCR1 induces autophagosome formation
edited	[InstanceEdit:9970206] Stephan, Ralf, 2025-10-29
eventOf	[Pathway:R-HSA-9918485] Dengue Virus Attachment and Entry - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:9016069] autophagosome-endosome fusion
input	[Complex:R-HSA-9922606] DENV-2 virion:HAVCR1 [endosome membrane]
isChimeric	false
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:9945914] TIM-1 As a Signal Receptor Triggers Dengue Virus-Induced Autophagy [LiteratureReference:9945946] Single-virus tracking approach to reveal the interaction of Dengue virus with autophagy during the early stage of infection [LiteratureReference:9945949] Dengue virus and autophagy [LiteratureReference:9945986] Lipophagy: Molecular Mechanisms and Implications in Metabolic Disorders [LiteratureReference:9947547] Dengue virus induced autophagy is mediated by HMGB1 and promotes viral propagation [LiteratureReference:9947583] Mechanism of autophagy induced by activation of the AMPK/ERK/mTOR signaling pathway after TRIM22-mediated DENV-2 infection of HUVECs [LiteratureReference:9947734] Orthoflavivirus infection and the mTOR signaling pathway [LiteratureReference:9948284] Role of autophagy during the replication and pathogenesis of common mosquito-borne flavi- and alphaviruses
maxDepth	1
modified	[InstanceEdit:9970472] Stephan, Ralf, 2025-10-30
name	Dengue virion:HAVCR1 induces autophagosome formation
output	[Complex:R-HSA-9945920] DENV-2 virion:HAVCR1 [autophagosome membrane]
precedingEvent	[BlackBoxEvent:R-HSA-9922480] Dengue virion gets internalized - Homo sapiens
regulatedBy	[Requirement:9945932] Requirement by 'PIK3R1 [cytosol]'
relatedSpecies	[Species:3244621] Dengue virus type 2
releaseDate	2025-12-08
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9970204] Mansur, Daniel Santos, 2025-10-29 [InstanceEdit:9970439] Roque Ascen��o, Fernando, 2025-10-29
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9945936
summation	[Summation:9945922] DENV-containing endosomes deliver DENV to autophagosomes (Ch...

Referrals

(hasEvent)

[Pathway:R-HSA-9918485] Dengue Virus Attachment and Entry

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