Reactome | BTRC,FBWX11:CUL1:RBX1:SKP1 [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-9932521] BTRC,FBXW11:CUL1:RBX1:SKP1:p-S-PER1,2,3 [cytosol] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9932506] BTRC:CUL1:SKP1:RBX1 binds phosphorylated PER protein - Homo sapiens
created	[InstanceEdit:9935061] May, Bruce, 2025-01-12
dbId	9935060
displayName	BTRC,FBWX11:CUL1:RBX1:SKP1 [cytosol]
hasComponent	[DefinedSet:R-HSA-5607666] beta-TrCP [cytosol] [EntityWithAccessionedSequence:R-HSA-174230] CUL1 [cytosol] [EntityWithAccessionedSequence:R-HSA-180582] RBX1 [cytosol] [EntityWithAccessionedSequence:R-HSA-174150] SKP1 [cytosol]
inDisease	false
maxDepth	3
name	BTRC,FBWX11:CUL1:RBX1:SKP1 SCF beta-TrCP complex beta-TrCP:Skp1:Cul1:Rbx1
producedByEvent	[BlackBoxEvent:R-HSA-9932510] BTRC:CUL1:SKP1:RBX1 (SCF-beta-TrCP1) ubiquitinylates phosphorylated PER1,2,3 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9935060

(input)	[Reaction:R-HSA-9932506] BTRC:CUL1:SKP1:RBX1 binds phosphorylated PER protein
(output)	[BlackBoxEvent:R-HSA-9932510] BTRC:CUL1:SKP1:RBX1 (SCF-beta-TrCP1) ubiquitinylates phosphorylated PER1,2,3
(hasComponent)	[Complex:R-HSA-9932521] BTRC,FBXW11:CUL1:RBX1:SKP1:p-S-PER1,2,3 [cytosol]
(activeUnit)	[CatalystActivity:9932524] ubiquitin protein ligase activity of BTRC,FBXW11:CUL1:RBX1:SKP1:p-S-PER1,2,3 [cytosol]

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