Reactome | Late core complex dimer binds UQCR10, UQCR11, UQCRFS1.

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Late core complex dimer binds UQCR10, UQCR11, UQCRFS1. Show undefined attributes

authored	[InstanceEdit:9866163] Stephan, Ralf, 2024-03-23
category	binding
compartment	[Compartment:70616] mitochondrial inner membrane
created	[InstanceEdit:9866167] Stephan, Ralf, 2024-03-23
dbId	9866164
displayName	Late core complex dimer binds UQCR10, UQCR11, UQCRFS1.
edited	[InstanceEdit:9910822] Stephan, Ralf, 2024-05-21
eventOf	[Pathway:R-HSA-9865881] Complex III assembly - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-9906017] Unknown peptidase cleaves UQCRFS1 subunit - Homo sapiens
inferredFrom	[Reaction:R-SCE-9866165] Late core complex dimer binds QCR9. QCR10, RIP1 - Saccharomyces cerevisiae
input	2 × [Complex:R-HSA-164304] holo-UQCRFS1(1-274) [mitochondrial inner membrane] [Complex:R-HSA-9866174] Late core complex dimer [mitochondrial inner membrane] 2 × [EntityWithAccessionedSequence:R-HSA-164282] UQCR10 [mitochondrial inner membrane] 2 × [EntityWithAccessionedSequence:R-HSA-164285] UQCR11 [mitochondrial inner membrane]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:9865877] Biogenesis of the bc₁ Complex of the Mitochondrial Respiratory Chain [LiteratureReference:9865886] Assembly of the Multi-Subunit Cytochrome bc₁ Complex in the Yeast Saccharomyces cerevisiae [LiteratureReference:9866083] Architecture of Human Mitochondrial Respiratory Megacomplex I₂III₂IV₂
maxDepth	1
modified	[InstanceEdit:9933039] Stephan, Ralf, 2024-12-23
name	Late core complex dimer binds UQCR10, UQCR11, UQCRFS1.
output	[Complex:R-HSA-9906021] Dimer of Late core complex:UQCR10:UQCR11:holo-UQCRFS1(1-274) [mitochondrial inner membrane]
precedingEvent	[Reaction:R-HSA-9866162] Late core complex dimerizes - Homo sapiens [Reaction:R-HSA-9866272] 2Fe-2S is inserted in UQCRFS1 - Homo sapiens
previousReviewStatus	[ReviewStatus:9821383] three stars
regulatedBy	[Requirement:9866296] Requirement by 'BCS1L:LETM hexamer [mitochondrial inner membrane]'
regulationReference	[RegulationReference:9866299] Requirement by 'BCS1L:LETM hexamer [mitochondrial inner membrane]' Bcs1p, an AAA-family member, is a chaperone for the assembly of the cytochrome bc(1) complex
releaseDate	2024-06-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9910688] Hill, David P, 2024-05-16
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9866164
summation	[Summation:9866202] Binding of UQCR10, UQCR11, and UQCRFS1 to the late core comp...

Referrals

(hasEvent)	[Pathway:R-HSA-9865881] Complex III assembly
(precedingEvent)	[BlackBoxEvent:R-HSA-9906017] Unknown peptidase cleaves UQCRFS1 subunit
(inferredTo)	[Reaction:R-SCE-9866165] Late core complex dimer binds QCR9. QCR10, RIP1

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