Reactome | TRPV4 tetramer:CALM1:Ca2+ [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:9858793] calcium channel activity of TRPV4 tetramer:CALM1:Ca2+ [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9865672] May, Bruce, 2024-03-17
dbId	9865674
displayName	TRPV4 tetramer:CALM1:Ca2+ [plasma membrane]
hasComponent	4 × [Complex:R-HSA-74294] CALM1:4xCa2+ [cytosol] [Complex:R-HSA-9858825] TRPV4 tetramer [plasma membrane]
inDisease	false
includedLocation	[Compartment:70101] cytosol
inferredTo	[Complex:R-MMU-9865674] TRPV4 tetramer:CALM1:Ca2+ [plasma membrane] - Mus musculus [Complex:R-RNO-9865674] TRPV4 tetramer:CALM1:Ca2+ [plasma membrane] - Rattus norvegicus [Complex:R-CFA-9865674] TRPV4 tetramer:CALM1:Ca2+ [plasma membrane] - Canis familiaris [Complex:R-BTA-9865674] TRPV4 tetramer:CALM1:Ca2+ [plasma membrane] - Bos taurus [Complex:R-DME-9865674] TRPV4 tetramer:CALM1:Ca2+ [plasma membrane] - Drosophila melanogaster [Complex:R-CEL-9865674] TRPV4 tetramer:CALM1:Ca2+ [plasma membrane] - Caenorhabditis elegans
isChimeric	false
literatureReference	[LiteratureReference:9863414] Ca2+-dependent potentiation of the nonselective cation channel TRPV4 is mediated by a C-terminal calmodulin binding site
maxDepth	3
modified	[InstanceEdit:9916080] May, Bruce, 2024-07-22
name	TRPV4 tetramer:CALM1:Ca2+
producedByEvent	[Reaction:R-HSA-9865670] TRPV4 tetramer binds CALM1:Ca2+ (calmodulin:Ca2+) - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9865674

(output)	[Reaction:R-HSA-9865670] TRPV4 tetramer binds CALM1:Ca2+ (calmodulin:Ca2+)
(physicalEntity)	[CatalystActivity:9858793] calcium channel activity of TRPV4 tetramer:CALM1:Ca2+ [plasma membrane]

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