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Entries
MITF-M dimer binds the BIRC7 promoter
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authored
[InstanceEdit:9856650] Rothfels, Karen, 2023-12-21
category
binding
compartment
[Compartment:7660] nucleoplasm
created
[InstanceEdit:9857372] Rothfels, Karen, 2024-01-04
dbId
9857359
displayName
MITF-M dimer binds the BIRC7 promoter
edited
[InstanceEdit:9856650] Rothfels, Karen, 2023-12-21
eventOf
[Pathway:R-HSA-9824594] Regulation of MITF-M-dependent genes involved in apoptosis - Homo sapiens
followingEvent
[BlackBoxEvent:R-HSA-9857365] MITF-M-dependent BIRC7 gene expression - Homo sapiens
input
[EntityWithAccessionedSequence:R-HSA-9857352] BIRC7 gene [nucleoplasm]
[Complex:R-HSA-9825710] MITF-M dimer [nucleoplasm]
isChimeric
false
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:9856949] Microphthalmia-associated transcription factor is a critical transcriptional regulator of melanoma inhibitor of apoptosis in melanomas
[LiteratureReference:9854815] Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma
[LiteratureReference:9857148] Livin/ML-IAP as a new target for cancer treatment
[LiteratureReference:9857141] Inhibitors of apoptotic proteins: new targets for anticancer therapy
[LiteratureReference:9730403] MITF-the first 25 years
maxDepth
1
modified
[InstanceEdit:9927681] Rothfels, Karen, 2024-11-08
name
MITF-M dimer binds the BIRC7 promoter
output
[Complex:R-HSA-9857356] MITF-M dimer:BIRC7gene [nucleoplasm]
precedingEvent
[Reaction:R-HSA-9857375] MITF dimerizes - Homo sapiens
previousReviewStatus
[ReviewStatus:9821383] three stars
releaseDate
2024-03-27
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:9863245] Arnheiter, Heinz, 2024-02-26
[InstanceEdit:9910860] de la Serna, Ivana L, 2024-05-21
[InstanceEdit:9927254] Vu, Hong Nhung, 2024-11-05
[InstanceEdit:9927252] Steingrímsson, Eiríkur, 2024-11-05
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-9857359
summation
[Summation:9857346] MITF-M binds to two consensus elements in the promoter of th...
Referrals
(hasEvent)
[Pathway:R-HSA-9824594] Regulation of MITF-M-dependent genes involved in apoptosis
(precedingEvent)
[BlackBoxEvent:R-HSA-9857365] MITF-M-dependent BIRC7 gene expression
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