Reactome | Unknown enzyme(s) process 4-HMA to 4-Hbz

Schema > Reaction > Entries

Unknown enzyme(s) process 4-HMA to 4-Hbz Show undefined attributes

authored	[InstanceEdit:9856699] Stephan, Ralf, 2023-12-22
catalystActivity	[CatalystActivity:9949579] carboxy-lyase activity of Unknown carboxylyase [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:9856736] Stephan, Ralf, 2023-12-22
dbId	9856737
displayName	Unknown enzyme(s) process 4-HMA to 4-Hbz
edited	[InstanceEdit:9910825] Stephan, Ralf, 2024-05-21
eventOf	[Pathway:R-HSA-2142789] Ubiquinol biosynthesis - Homo sapiens
followingEvent	[Reaction:R-HSA-9856794] Unknown dehydrogenase oxidizes 4-HBz - Homo sapiens
input	[SimpleEntity:R-ALL-9856722] 4-HMA [mitochondrial matrix]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9856597] Biosynthesis, Deficiency, and Supplementation of Coenzyme Q [LiteratureReference:9856710] The polar oxy-metabolome reveals the 4-hydroxymandelate CoQ10 synthesis pathway [LiteratureReference:9856852] Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis [LiteratureReference:9856854] Structure, substrate specificity, and catalytic mechanism of human D-2-HGDH and insights into pathogenicity of disease-associated mutations [LiteratureReference:9856856] The Mandelate Pathway, an Alternative to the Phenylalanine Ammonia Lyase Pathway for the Synthesis of Benzenoids in Ascomycete Yeasts [LiteratureReference:9856865] Coenzyme Q Biosynthesis: An Update on the Origins of the Benzenoid Ring and Discovery of New Ring Precursors
maxDepth	1
modified	[InstanceEdit:9962971] D'Eustachio, Peter, 2025-08-12
name	Unknown enzyme(s) process 4-HMA to 4-Hbz
output	[SimpleEntity:R-ALL-9856800] 4-Hbz [mitochondrial matrix]
precedingEvent	[Reaction:R-HSA-9856718] HPDL dioxygenates HPPA - Homo sapiens
previousReviewStatus	[ReviewStatus:9821385] four stars
releaseDate	2024-06-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9909268] Pierrel, Fabien, 2024-05-02 [InstanceEdit:9909593] Marchi, Marco, 2024-05-14 [InstanceEdit:9910563] Tonello, Fiorella, 2024-05-15 [InstanceEdit:9962972] Hill, David P, 2025-08-12
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9856737
summation	[Summation:9856859] It is unknown how (S)-4-hydroxymandelate (4-HMA) gets proces...
updateTrackers	[UpdateTracker:9953689] Update Tracker - [Reaction:9856737] Unknown enzyme(s) process 4-HMA to 4-Hbz - v93:[removeCatalystActivity]

Referrals

(updatedInstance)	[UpdateTracker:9953689] Update Tracker - [Reaction:9856737] Unknown enzyme(s) process 4-HMA to 4-Hbz - v93:[removeCatalystActivity]
(hasEvent)	[Pathway:R-HSA-2142789] Ubiquinol biosynthesis
(precedingEvent)	[Reaction:R-HSA-9856794] Unknown dehydrogenase oxidizes 4-HBz