Reactome | FIRRM:FIGNL1 [nucleoplasm]

Schema > Complex > Entries

FIRRM:FIGNL1 [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-9853879] FIRRM:FIGNL1:DMC1, RAD51 [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9853878] FIGNL1 binds DMC1, RAD51 - Homo sapiens [Reaction:R-HSA-9853389] FIGNL1 binds RAD51 - Homo sapiens [Reaction:R-HSA-9853376] FIGNL1 binds SPIDR - Homo sapiens
created	[InstanceEdit:9853378] Orlic-Milacic, Marija, 2023-11-15
dbId	9853380
displayName	FIRRM:FIGNL1 [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-HSA-9853365] FIGNL1 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-9853387] FIRRM [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-9853380] FIRRM:FIGNL1 [nucleoplasm] - Mus musculus [Complex:R-RNO-9853380] FIRRM:FIGNL1 [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-9853380] FIRRM:FIGNL1 [nucleoplasm] - Canis familiaris [Complex:R-BTA-9853380] FIRRM:FIGNL1 [nucleoplasm] - Bos taurus [Complex:R-SSC-9853380] FIRRM:FIGNL1 [nucleoplasm] - Sus scrofa [Complex:R-DRE-9853380] FIRRM:FIGNL1 [nucleoplasm] - Danio rerio [Complex:R-GGA-9853380] FIRRM:FIGNL1 [nucleoplasm] - Gallus gallus
isChimeric	false
literatureReference	[LiteratureReference:9853366] FIGL1 and its novel partner FLIP form a conserved complex that regulates homologous recombination [LiteratureReference:9853381] FIGNL1-containing protein complex is required for efficient homologous recombination repair
maxDepth	2
name	FIRRM:FIGNL1
producedByEvent	[Reaction:R-HSA-9853368] FIRRM binds FIGNL1 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9853380

Referrals

(hasComponent)	[Complex:R-HSA-9853879] FIRRM:FIGNL1:DMC1, RAD51 [nucleoplasm] [Complex:R-HSA-9853704] FIRRM:FIGNL1:SPIDR [nucleoplasm] [Complex:R-HSA-9853700] Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:FIRRM:FIGNL1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm]
(input)	[Reaction:R-HSA-9853878] FIGNL1 binds DMC1, RAD51 [Reaction:R-HSA-9853389] FIGNL1 binds RAD51 [Reaction:R-HSA-9853376] FIGNL1 binds SPIDR
(output)	[Reaction:R-HSA-9853368] FIRRM binds FIGNL1
(activeUnit)	[PositiveRegulation:9853711] Positive regulation by 'FIRRM:FIGNL1:SPIDR [nucleoplasm]' [PositiveRegulation:9853710] Positive regulation by 'Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:FIRRM:FIGNL1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm]'

© 2026 Reactome

Cite Us!