Reactome | pY705, S727-STAT3 dimer:IRF4 gene [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9850946] Rothfels, Karen, 2023-10-12
crossReference	[DatabaseIdentifier:12020842] Mondo:0020325
dbId	9850945
disease	[Disease:9699595] anaplastic large cell lymphoma [Disease:1500689] cancer
displayName	pY705, S727-STAT3 dimer:IRF4 gene [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-HSA-8948472] IRF4 gene [nucleoplasm] [Complex:R-HSA-9701457] p-Y705,S727-STAT3 dimer [nucleoplasm]
inDisease	true
isChimeric	false
maxDepth	3
name	pY705, S727-STAT3 dimer:IRF4 gene
positivelyRegulates	[PositiveGeneExpressionRegulation:9850995] Positive gene expression regulation by 'pY705, S727-STAT3 dimer:IRF4 gene [nucleoplasm]'
producedByEvent	[Reaction:R-HSA-9851118] pY-STAT3 binds the IRF4 promoter downstream of NPM1-ALK - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9850945

(regulator)	[PositiveGeneExpressionRegulation:9850995] Positive gene expression regulation by 'pY705, S727-STAT3 dimer:IRF4 gene [nucleoplasm]'
(output)	[Reaction:R-HSA-9851118] pY-STAT3 binds the IRF4 promoter downstream of NPM1-ALK

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