Reactome | Defective binding of VWF variant to GPIb:IX:V

Schema > Pathway > Entries

authored	[InstanceEdit:9823584] Shamovsky, Veronica, 2023-01-07
created	[InstanceEdit:9846299] Shamovsky, Veronica, 2023-10-10
crossReference	[DatabaseIdentifier:12020796] Mondo:0000009
dbId	9846298
disease	[Disease:9705355] blood platelet disease
displayName	Defective binding of VWF variant to GPIb:IX:V
edited	[InstanceEdit:9852766] Shamovsky, Veronica, 2023-11-07
eventOf	[Pathway:R-HSA-9823587] Defects of platelet adhesion to exposed collagen - Homo sapiens
hasDiagram	true
hasEHLD	false
hasEvent	[FailedReaction:R-HSA-9823706] VWF variant does not bind GPIb:IX:V - Homo sapiens
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:9823712] Variability in platelet- and collagen-binding defects in type 2M von Willebrand disease
maxDepth	2
modified	[InstanceEdit:9852913] Shamovsky, Veronica, 2023-11-07
name	Defective binding of VWF variant to GPIb:IX:V
normalPathway	[Pathway:R-HSA-75892] Platelet Adhesion to exposed collagen
releaseDate	2023-12-06
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9852868] Gao, Rui, 2023-11-06
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-9846298
summation	[Summation:9846300] This Reactome event describes von Willebrand disease (VWD)-a...

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