Reactome | APP [mitochondrial inner membrane]

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APP [mitochondrial inner membrane] Show undefined attributes

compartment	[Compartment:70616] mitochondrial inner membrane
consumedByEvent	[BlackBoxEvent:R-HSA-9839072] HTRA2 degrades APP (Amyloid-beta precursor protein) - Homo sapiens
created	[InstanceEdit:9839143] May, Bruce, 2023-06-30
dbId	9839060
displayName	APP [mitochondrial inner membrane]
endCoordinate	695
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-9839060] APP [mitochondrial inner membrane] - Mus musculus [EntityWithAccessionedSequence:R-RNO-9839060] APP [mitochondrial inner membrane] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-9839060] APP [mitochondrial inner membrane] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-9839060] APP [mitochondrial inner membrane] - Bos taurus [EntityWithAccessionedSequence:R-SSC-9839060] APP [mitochondrial inner membrane] - Sus scrofa [EntityWithAccessionedSequence:R-SSC-9839060-2] APP [mitochondrial inner membrane] - Sus scrofa [DefinedSet:R-SSC-9839060-3] Homologues of APP [mitochondrial inner membrane] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-9839060] appa [mitochondrial inner membrane] - Danio rerio [EntityWithAccessionedSequence:R-XTR-9839060] app [mitochondrial inner membrane] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-9839060] APP [mitochondrial inner membrane] - Gallus gallus [EntityWithAccessionedSequence:R-DME-9839060] Appl [mitochondrial inner membrane] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-9839060] APP [mitochondrial inner membrane] - Caenorhabditis elegans
literatureReference	[LiteratureReference:9839085] Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells [LiteratureReference:9839123] Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction
maxDepth	1
name	APP fullName evidence="150"Amyloid-beta precursor protein A4_HUMAN APP695
referenceEntity	[ReferenceIsoform:uniprot:P05067-4] UniProt:P05067-4 APP
referenceType	ReferenceIsoform
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9839060
startCoordinate	18

Referrals

(input)

[BlackBoxEvent:R-HSA-9839072] HTRA2 degrades APP (Amyloid-beta precursor protein)

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