Reactome | BLNK:GRB2:SOS1:CIN85 [cytosol]

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BLNK:GRB2:SOS1:CIN85 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
consumedByEvent	[Reaction:R-HSA-983703] p-6Y-SYK phosphorylates BLNK (SLP65) - Homo sapiens
created	[InstanceEdit:983685] May, B, 2010-11-02
dbId	983692
displayName	BLNK:GRB2:SOS1:CIN85 [cytosol]
hasComponent	[EntityWithAccessionedSequence:R-HSA-912750] BLNK [cytosol] [EntityWithAccessionedSequence:R-HSA-74686] GRB2-1 [cytosol] [EntityWithAccessionedSequence:R-HSA-182957] SH3KBP1 [cytosol] [EntityWithAccessionedSequence:R-HSA-64847] SOS1 [cytosol]
inDisease	false
inferredTo	[Complex:R-MMU-983692] BLNK:GRB2:SOS1:CIN85 [cytosol] - Mus musculus [Complex:R-RNO-983692] BLNK:GRB2:SOS1:CIN85 [cytosol] - Rattus norvegicus [Complex:R-CFA-983692] BLNK:GRB2:SOS1:CIN85 [cytosol] - Canis familiaris [Complex:R-BTA-983692] BLNK:GRB2:SOS1:CIN85 [cytosol] - Bos taurus [Complex:R-SSC-983692] BLNK:GRB2:SOS1:CIN85 [cytosol] - Sus scrofa
isChimeric	false
literatureReference	[LiteratureReference:983502] BLNK: a central linker protein in B cell activation [LiteratureReference:2076207] The B-cell antigen receptor signals through a preformed transducer module of SLP65 and CIN85 [LiteratureReference:2076226] Characterization of the CIN85 adaptor protein and identification of components involved in CIN85 complexes [LiteratureReference:2089916] CIN85 is required for Cbl-mediated regulation of antigen receptor signaling in human B cells
maxDepth	2
modified	[InstanceEdit:9613687] May, Bruce, 2018-07-18
name	BLNK:GRB2:SOS1:CIN85
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-983692
updateTrackers	[UpdateTracker:9899469] Update Tracker - [Complex:983692] BLNK:GRB2:SOS1:CIN85 [cytosol] - v66:[modifyName, removeHasComponent]

Referrals

(updatedInstance)	[UpdateTracker:9899469] Update Tracker - [Complex:983692] BLNK:GRB2:SOS1:CIN85 [cytosol] - v66:[modifyName, removeHasComponent]
(input)	[Reaction:R-HSA-983703] p-6Y-SYK phosphorylates BLNK (SLP65)

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