Reactome | Protein P tetramer binds protein L

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Protein P tetramer binds protein L Show undefined attributes

authored	[InstanceEdit:9830230] Orlic-Milacic, Marija, 2023-02-28
category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9830230] Orlic-Milacic, Marija, 2023-02-28
crossReference	[DatabaseIdentifier:12020771] Mondo:0001577
dbId	9830236
disease	[Disease:9833927] respiratory syncytial virus infectious disease
displayName	Protein P tetramer binds protein L
edited	[InstanceEdit:9853005] Orlic-Milacic, Marija, 2023-11-09
eventOf	[Pathway:R-HSA-9828806] Maturation of hRSV A proteins - Homo sapiens
followingEvent	[Reaction:R-HSA-9830284] Protein M2-1 tetramers bind protein P tetramer - Homo sapiens
input	[Complex:R-RSY-9831482] L:Mg2+ [cytosol] [Complex:R-RSY-9825430] P tetramer [cytosol]
isChimeric	false
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:9830241] Structure of the Respiratory Syncytial Virus Polymerase Complex [LiteratureReference:9825438] Cryo-EM structure of the respiratory syncytial virus RNA polymerase [LiteratureReference:9838557] Fine mapping and characterization of the L-polymerase-binding domain of the respiratory syncytial virus phosphoprotein
maxDepth	1
modified	[InstanceEdit:9853009] Orlic-Milacic, Marija, 2023-11-09
name	Protein P tetramer binds protein L
output	[Complex:R-RSY-9830228] RdRP [cytosol]
precedingEvent	[Reaction:R-HSA-9825422] P protein oligomerizes - Homo sapiens [BlackBoxEvent:R-HSA-9828719] L mRNA is translated into protein L - Homo sapiens
relatedSpecies	[Species:9717528] Human respiratory syncytial virus A
releaseDate	2023-12-06
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9852848] Bergeron, Harrison Christopher, 2023-11-03
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9830236
summation	[Summation:9830248] Protein P tetramer forms a complex with protein L, the RNA-d...

Referrals

(precedingEvent)	[Reaction:R-HSA-9830284] Protein M2-1 tetramers bind protein P tetramer
(hasEvent)	[Pathway:R-HSA-9828806] Maturation of hRSV A proteins

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