Reactome | MSGN1 and LEF1:CTNNB1 bind the DLL1 gene in presomitic mesoderm

Schema > Reaction > Entries

MSGN1 and LEF1:CTNNB1 bind the DLL1 gene in presomitic mesoderm Show undefined attributes

authored	[InstanceEdit:9820524] Chalamalasetty, Ravindra B, 2022-11-09 [InstanceEdit:9820530] Yamaguchi, Terry P, 2022-11-09
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9824212] May, Bruce, 2023-01-18
dbId	9824236
displayName	MSGN1 and LEF1:CTNNB1 bind the DLL1 gene in presomitic mesoderm
edited	[InstanceEdit:9824085] May, Bruce, 2023-01-14
eventOf	[Pathway:R-HSA-9824272] Somitogenesis - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-9825275] Expression of DLL1 in presomitic mesoderm - Homo sapiens
inferredFrom	[Reaction:R-MMU-9824277] Msgn1 and Lef1:Ctnnb1 bind the Dll1 gene in presomitic mesoderm - Mus musculus
input	[EntityWithAccessionedSequence:R-HSA-9023392] DLL1 gene [nucleoplasm] [Complex:R-HSA-9735197] LEF1:CTNNB1 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-9793376] MSGN1 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9835282] May, Bruce, 2023-05-12
name	MSGN1 and LEF1:CTNNB1 bind the DLL1 gene in presomitic mesoderm
output	[Complex:R-HSA-9824208] MSGN1:LEF1:CTNNB1:DLL1 gene [nucleoplasm]
precedingEvent	[Reaction:R-HSA-3299569] Beta-catenin displaces TLE:HDAC1 from TCF/LEF - Homo sapiens [BlackBoxEvent:R-HSA-9793375] Expression of MSGN1 in paraxial mesoderm - Homo sapiens
releaseDate	2023-06-07
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9835280] May, Bruce, 2023-05-12
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9824236
summation	[Summation:9825278] LEF1 and CTNNB1 (beta-catenin) activated by WNT signaling bi...

Referrals

(hasEvent)	[Pathway:R-HSA-9824272] Somitogenesis
(precedingEvent)	[BlackBoxEvent:R-HSA-9825275] Expression of DLL1 in presomitic mesoderm
(inferredTo)	[Reaction:R-MMU-9824277] Msgn1 and Lef1:Ctnnb1 bind the Dll1 gene in presomitic mesoderm

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